Jürgen Floege Selected Research

platelet-derived growth factor C (PDGF-C)

1/2019	Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.
1/2018	PDGF in organ fibrosis.
8/2015	Role of platelet-derived growth factor-CC in capillary rarefaction in renal fibrosis.
1/2013	Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis.
7/2010	PDGF-C mediates glomerular capillary repair.
10/2008	Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.
2/2008	PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.
1/2008	A new look at platelet-derived growth factor in renal disease.
5/2003	PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases.
4/2002	Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney.

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Jürgen Floege Research Topics

Disease

43	Chronic Renal Insufficiency 10/2022 - 06/2009
41	IGA Glomerulonephritis (IGA Nephropathy) 01/2022 - 05/2003
34	Fibrosis (Cirrhosis) 01/2021 - 03/2005
32	Glomerulonephritis 02/2020 - 02/2000
28	Proteinuria 10/2022 - 04/2000
23	Kidney Diseases (Kidney Disease) 01/2022 - 05/2008
21	Vascular Calcification 01/2022 - 01/2002
21	Inflammation (Inflammations) 11/2020 - 08/2004
21	Secondary Hyperparathyroidism 01/2019 - 09/2007
19	Chronic Kidney Failure (Chronic Renal Failure) 11/2021 - 08/2004
17	Renal Insufficiency (Renal Failure) 05/2022 - 11/2002
17	Nephritis 04/2021 - 08/2000
12	Hyperphosphatemia 10/2022 - 01/2002
10	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 12/2012
9	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 01/2020 - 12/2011
8	Heart Failure 10/2022 - 09/2007
8	Atrial Fibrillation 04/2022 - 11/2009
8	Albuminuria 01/2021 - 05/2002
7	Infections 01/2022 - 07/2007
7	Membranous Glomerulonephritis (Membranous Nephropathy) 10/2021 - 04/2002
6	Hemorrhage 01/2022 - 11/2002
6	Vitamin K Deficiency 01/2022 - 02/2011
6	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 10/2021 - 04/2006
6	Bone Diseases (Bone Disease) 01/2021 - 05/2008
5	Uremia 01/2022 - 05/2003
5	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 10/2021 - 05/2003
5	Ischemia 01/2020 - 10/2005
5	Hypertension (High Blood Pressure) 01/2020 - 08/2009
5	Ureteral Obstruction 01/2020 - 01/2013
5	Atherosclerosis 01/2020 - 01/2008
4	COVID-19 01/2022 - 03/2021
4	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 09/2011
4	Lupus Nephritis 10/2021 - 09/2009
4	Disease Progression 01/2020 - 04/2013
4	Sclerosis 01/2020 - 04/2002
4	Neoplasms (Cancer) 01/2019 - 01/2008
4	Hyperparathyroidism 01/2018 - 04/2011
3	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2007
3	Hypocalcemia 08/2020 - 12/2012
3	Diabetes Mellitus 08/2020 - 08/2004
3	Calciphylaxis 01/2020 - 03/2013
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 03/2012
3	Diarrhea 10/2018 - 09/2014
3	Constipation 10/2018 - 09/2014

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
22	MineralsIBA 10/2022 - 01/2008
21	Phosphates (Orthophosphate)IBA 01/2022 - 01/2002
18	Cinacalcet (Sensipar)FDA Link 08/2020 - 09/2007
16	Biomarkers (Surrogate Marker)IBA 10/2022 - 07/2011
16	CalciumIBA 08/2020 - 01/2002
14	Vitamin K FDA Link 04/2022 - 04/2009
10	platelet-derived growth factor C (PDGF-C)IBA 01/2019 - 04/2002
9	Vitamin D FDA LinkGeneric 08/2020 - 06/2010
9	Sevelamer (RenaGel)FDA Link 06/2020 - 08/2004
9	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 03/2002
8	CreatinineIBA 10/2022 - 03/2006
8	CollagenIBA 01/2022 - 05/2007
8	Parathyroid Hormone (Parathormone)IBA 01/2021 - 06/2010
8	sucroferric oxyhydroxideIBA 06/2020 - 06/2015
8	Platelet-Derived Growth FactorIBA 01/2018 - 03/2002
8	alpha-2-HS-GlycoproteinIBA 11/2013 - 03/2003
7	CytokinesIBA 01/2020 - 03/2005
7	Phosphorus (Red Phosphorus)IBA 10/2018 - 08/2004
7	Messenger RNA (mRNA)IBA 01/2018 - 09/2003
7	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 01/2008
6	AnticoagulantsIBA 04/2022 - 03/2013
6	Matrix Gla ProteinIBA 08/2014 - 01/2002
5	GlucocorticoidsIBA 01/2022 - 12/2011
5	SodiumIBA 01/2021 - 05/2008
5	Immunoglobulin A (IgA)IBA 01/2018 - 01/2009
4	Warfarin (Coumadin)FDA LinkGeneric 04/2022 - 01/2014
4	SteroidsIBA 12/2021 - 09/2011
4	Pharmaceutical PreparationsIBA 12/2021 - 12/2012
4	Calcineurin InhibitorsIBA 01/2021 - 07/2011
4	AntibodiesIBA 01/2021 - 12/2009
4	C-Reactive ProteinIBA 01/2021 - 08/2009
4	SterolsIBA 08/2020 - 04/2011
4	MagnesiumIBA 06/2020 - 06/2015
4	Biological ProductsIBA 01/2020 - 03/2005
4	Collagen Type I (Type I Collagen)IBA 01/2020 - 05/2007
4	Adenine FDA LinkGeneric 01/2020 - 12/2013
4	LigandsIBA 01/2018 - 09/2012
4	Protein Isoforms (Isoforms)IBA 11/2014 - 01/2008
3	omega-Chloroacetophenone (Mace)IBA 10/2022 - 08/2009
3	AlbuminsIBA 10/2022 - 05/2016
3	Vitamin K 2 (Vitamin K2)IBA 01/2022 - 02/2012
3	Methylprednisolone FDA LinkGeneric 01/2022 - 01/2017
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 10/2021 - 09/2009
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2020 - 10/2008
3	IronIBA 01/2020 - 07/2018
3	Complement System Proteins (Complement)IBA 01/2019 - 05/2016
3	Glycoproteins (Glycoprotein)IBA 11/2018 - 01/2002

Therapy/Procedure

40	Therapeutics 04/2022 - 06/2005
26	Renal Dialysis (Hemodialysis) 03/2021 - 07/2007
9	Nephrectomy 01/2022 - 06/2007
9	Kidney Transplantation 01/2021 - 07/2003
5	Transplantation 01/2021 - 05/2004
3	Peritoneal Dialysis 06/2021 - 09/2014
3	Catheters 08/2020 - 07/2007
3	Ligation 01/2020 - 05/2007